學習基礎核酸化學、基因的複製轉錄轉譯、基因的表現與調控、基因體學概念，以及基因操作技術原理，奠定未來從事生物技術研究或工作的基礎。本課程以對分子生物學內容具有興趣或研究工作有相關之同學為對象，提供分子生物學基本概念並熟悉與了解相關的研究進展與實驗技術。以分子層次的觀點對基因及其相關的活性，作一有系統及深入淺出的介紹。內容涵蓋DNA/RNA/蛋白質三個核心分子，除探討其合成複製及轉錄轉譯過程，也對分子間交互作用與調控修補維護等機制進行剖析。另外，也針對研究所需之相關技術配合實際應用詳加介紹，以帶領學習者進入基因體學及蛋白質體學的時代。Learn basic nucleic acid chemistry, gene replication, transcription and translation, gene expression and regulation, genomic concepts, and principles of gene manipulation techniques to lay the foundation for future biotechnology research or work. This course is aimed at students who are interested in molecular biology or have related research work. It provides basic concepts of molecular biology and familiarizes them with relevant research progress and experimental techniques. Provide a systematic and easy-to-understand introduction to genes and their related activities from a molecular level perspective. The content covers the three core molecules of DNA/RNA/protein. In addition to discussing their synthesis, replication, transcription and translation processes, it also analyzes the mechanisms of intermolecular interactions, regulation, repair and maintenance. In addition, relevant technologies required for research and practical applications are introduced in detail to lead learners into the era of genomics and proteomics.
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1.Molecular Biology by David P. Clark and Nanette J. Pazdernik. 2e. 2013. Elsevier Inc, USA. 中文導讀 王紹鴻 2014。
1.Molecular Biology by David P. Clark and Nanette J. Pazdernik. 2e. 2013. Elsevier Inc, USA. Chinese introduction Wang Shaohong 2014.
| 評分項目 Grading Method | 配分比例 Grading percentage | 說明 Description |
|---|---|---|
| 課後作業課後作業 Homework |
20 | 各章隨堂作業 |
| 學習態度學習態度 learning attitude |
10 | 上課出勤及學習狀況 |
| 期中考試期中考試 midterm exam |
35 | 筆試 |
| 期末考試期末考試 final exam |
35 | 筆試 |
