讓修課學生學習、瞭解並應用實驗動物模型在生物醫學研究與實驗動物之照護與管理，並在「3R原則」 ( The 3-R Concept )：取代 ( Replacement )，減量 ( Reduction )，精緻 ( Refinement )的要求下，適切的應用實驗動物。實驗動物模型為醫學及生命科學研究於人體臨床前之重要試驗，配合動物保護法與生命科學之研究，教授學生對實驗動物之應用與實驗動物福祉之保障。
在實驗動物的使用技術方面，主要強調如何杜絕一些不人道的動物實
驗，同時提出 「3R原則」 ( The 3-R Concept )：取代 ( Replacement )，減量 ( Reduction )，精緻 ( Refinement )，作為動物實驗時主要之指導原則。茲簡述於下：
一、 取代 ( Replacement )：利用體外實驗技術、電腦化模擬及錄影帶等技術，以取代活體實驗，並且可以得到相同的實驗結果及數據。
二、 減量 ( Reduction )：主要是減少實驗動物的使用量。利用適當的實驗方法、控制環境的變異數及統計學上的顯著性，可以在試驗設計上減少實驗動物的使用量，並且可以取得相同的實驗結果及數據。近來在實驗動物學上的進步，使動物的健康監測、遺傳特性及環境要求標準化，可以減少實驗上的變異數，而減低使用數量。
三、 精緻 ( Refinement )：減少實驗動物於實驗中產生的緊迫及疼痛。規劃動物試驗時，先行瞭解動物的需求、良好的飼養管理及環境需求，可以減少動物的緊迫。使用適當的麻醉劑、止痛劑以及合理的安樂死等，皆是精緻化的一部份。同時，實驗動物中心在營運上的改善，也可使動物實驗的飼養與管理更為人道。「精緻」不只可以增加動物之福祉，同時也可以保證動物實驗的品質。此外，進行動物實驗時，除了進行實驗之科學家之外，仍需要其他人員的配合，包括動物飼養管理人員、動物技術人員、實驗動物獸醫及專家等，才能達到這三項目標。
This course allows students to learn, understand and apply experimental animal models in biomedical research and the care and management of experimental animals, and practice the "3R principles" (The 3-R Concept): Replacement, Reduction, Refining ( Refinement), appropriate use of experimental animals. Experimental animal models are important preclinical tests for medical and life science research on humans. In conjunction with animal protection laws and life science research, students are taught the application of experimental animals and the protection of the welfare of experimental animals.
In terms of the use of experimental animals, the main emphasis is on how to put an end to some inhumane animal practices.
At the same time, "The 3-R Concept" (Replacement), Reduction (Reduction), and Refinement (Refinement) was proposed as the main guiding principle in animal experiments. It is briefly described below:
1. Replacement: Use in vitro experimental technology, computerized simulation, video tape and other technologies to replace in vivo experiments, and the same experimental results and data can be obtained.
2. Reduction: mainly reducing the use of experimental animals. By using appropriate experimental methods, controlling environmental variability and statistical significance, the number of experimental animals used can be reduced in experimental design and the same experimental results and data can be obtained. Recent advances in experimental zoology have standardized the health monitoring, genetic characteristics, and environmental requirements of animals, which can reduce experimental variability and reduce the number of animals used.
3. Refinement: Reduce the stress and pain caused by experimental animals during experiments. When planning animal testing, understanding the animal's needs, good husbandry, and environmental requirements can reduce stress on the animal. The use of appropriate anesthetics, analgesics, and appropriate euthanasia are all part of refinement. At the same time, improvements in the operations of experimental animal centers can also make the raising and management of animal experiments more humane. "Delicacy" not only increases the welfare of animals, but also ensures the quality of animal experiments. In addition, when conducting animal experiments, in addition to the scientists conducting the experiments, the cooperation of other personnel, including animal husbandry managers, animal technicians, experimental animal veterinarians, and experts, is still required to achieve these three goals.
實驗動物模型為醫學及生命科學研究於人體臨床前之重要試驗，配合動物保護法與生命科學之研究，教授學生對實驗動物之應用與動物福祉之保障。
Experimental animal models are important preclinical tests for medical and life science research on humans. In conjunction with animal protection laws and life science research, students are taught the application of experimental animals and the protection of animal welfare.
1. 實驗動物管理與使用指南編輯委員會. 實驗動物管理與使用指南. 2010. 中華民國實驗動物學會出版. 第三版 (擴充版).
2. http://animal.coa.gov.tw/html/download/labaratory/110524/39_download_all.pdf
1. Editorial Committee of the Guide for the Care and Use of Laboratory Animals. Guide for the Care and Use of Laboratory Animals. 2010. Published by the Society of Laboratory Animals of the Republic of China. Third Edition (Expanded Edition).
2. http://animal.coa.gov.tw/html/download/labaratory/110524/39_download_all.pdf
| 評分項目 Grading Method | 配分比例 Grading percentage | 說明 Description |
|---|---|---|
| 隨堂表現隨堂表現 Performance in class |
20 | 課堂表現、出席率 |
| 期中考期中考 midterm exam |
40 | 期中考 |
| 期末考期末考 final exam |
40 | 期末考 |
