對基本免疫學理論的介紹，包括生物體防禦系統與病原之間的關係與交互作用，及防禦系統的功能性缺陷等，透過對免疫學的了解，以培育對經濟動物、伴侶動物及人類健康維持的能力。
1. 本課程以建立動物科學、生物科技及生命科學領域學生之現代免疫學基礎知識與應用能力為目標，系統性介紹免疫系統的組成、功能與調控機制，培養學生理解宿主與病原互動、疾病發生機制及免疫調控策略之能力。課程內容涵蓋先天性免疫與適應性免疫之基本原理、抗原辨識與呈現、淋巴球活化與效應機制，以及免疫耐受、疫苗學與臨床免疫學等重要主題。
2. 課程首先介紹免疫系統的組成、免疫器官與細胞種類，以及先天免疫與適應性免疫之特性與差異，使學生建立免疫防禦的整體架構觀念。接續探討先天免疫中的模式辨識受體（PRRs）、發炎反應、吞噬作用、補體系統與自然殺手細胞（NK cells）等重要防禦機制，以及其在啟動後天免疫反應中的關鍵角色。
3. 在適應性免疫部分，課程深入說明主要組織相容性複合體（MHC）與抗原呈現機制、抗體與T細胞受體（TCR）之結構與功能、多樣性產生機制，以及B細胞與T細胞如何辨識抗原並啟動免疫反應。學生將學習細胞媒介免疫與體液免疫之活化、分化與效應機制，包括CD4⁺輔助型T細胞、CD8⁺細胞毒殺型T細胞、漿細胞及記憶細胞在免疫防禦中的功能。
4. 進一步介紹抗體效應功能、補體活化、黏膜免疫、母源抗體傳遞及宿主對病原微生物之防禦策略，並探討免疫系統如何維持自體耐受與免疫平衡。課程亦涵蓋自體免疫疾病、過敏反應、免疫缺陷疾病、腫瘤免疫學與移植免疫學等臨床相關議題，使學生了解免疫系統失衡所導致之疾病機制與治療策略。
5. 最後，課程介紹疫苗學與免疫調節應用，包括傳統疫苗與新世代核酸疫苗之設計原理、免疫保護機制及公共衛生意義，並延伸至動物與寵物科學領域之免疫調控策略，如營養免疫學、微生物相調節、單株抗體、生物製劑及精準免疫介入等新興應用。
6. 透過本課程之學習，學生將具備分析免疫反應機制、解釋免疫相關疾病、評估疫苗與免疫治療策略，以及將免疫學知識應用於動物健康、生物醫學研究、疾病防治與生物科技產業之能力，為未來進階研究或專業發展奠定堅實基礎。

An introduction to basic immunology theory, including the relationship and interaction between the organism's defense system and pathogens, as well as the functional defects of the defense system, etc., through the understanding of immunology, to cultivate the ability to maintain the health of economic animals, companion animals and humans.
1. This course aims to establish the basic knowledge and application ability of modern immunology for students in the fields of animal science, biotechnology and life sciences. It systematically introduces the composition, function and regulatory mechanism of the immune system, and cultivates students' ability to understand the interaction between host and pathogen, disease mechanisms and immune regulation strategies. The course content covers the basic principles of innate immunity and adaptive immunity, antigen recognition and presentation, lymphocyte activation and effector mechanisms, as well as important topics such as immune tolerance, vaccinology and clinical immunology.
2. The course first introduces the composition of the immune system, immune organs and cell types, as well as the characteristics and differences between innate immunity and adaptive immunity, allowing students to establish the overall architectural concept of immune defense. Continue to explore important defense mechanisms such as pattern recognition receptors (PRRs), inflammatory response, phagocytosis, complement system, and natural killer cells (NK cells) in innate immunity, as well as their key roles in initiating acquired immune responses.
3. In the adaptive immunity part, the course provides an in-depth explanation of the major histocompatibility complex (MHC) and antigen presentation mechanism, the structure and function of antibodies and T cell receptors (TCR), the mechanism of diversity generation, and how B cells and T cells recognize antigens and initiate immune responses. Students will learn the activation, differentiation and effector mechanisms of cell-mediated immunity and humoral immunity, including the functions of CD4⁺ helper T cells, CD8⁺ cytotoxic T cells, plasma cells and memory cells in immune defense.
4. Further introduce the antibody effector function, complement activation, mucosal immunity, maternal antibody transmission and host defense strategies against pathogenic microorganisms, and explore how the immune system maintains self-tolerance and immune balance. The course also covers clinically relevant topics such as autoimmune diseases, allergic reactions, immunodeficiency diseases, tumor immunology and transplantation immunology, allowing students to understand the disease mechanisms and treatment strategies caused by immune system imbalance.
5. Finally, the course introduces the application of vaccinology and immune regulation, including the design principles of traditional vaccines and new generation nucleic acid vaccines, immune protection mechanisms and public health significance, and extends to immune regulation strategies in the field of animal and pet science, such as nutritional immunology, microbial phase regulation, monoclonal antibodies, biological agents and precision immune intervention and other emerging applications.
6. Through the study of this course, students will have the ability to analyze immune response mechanisms, explain immune-related diseases, evaluate vaccines and immunotherapy strategies, and apply immunological knowledge to animal health, biomedical research, disease prevention and treatment, and biotechnology industries, laying a solid foundation for future advanced research or professional development.

課程將介紹基礎的免疫系統及其功能，包含先天性及適應性免疫反應、B淋巴細胞與T淋巴細胞之產生、免疫作用機轉、及免疫系統與健康和疾病之關聯等四大部分。首先介紹免疫系統之細胞、器官及先天性免疫系統，其次說明抗原、抗體、免疫球蛋白基因組成、抗原抗體反應、補體、主要組織相容複合體、抗原呈現、T細胞及B細胞之成熟、活化及分化等主題。課程後半則討論細胞激素、白血球活化及移動、細胞性毒殺反應、過敏反應、免疫耐受性及自體免疫。最後則探討移植、感染、疫苗、AIDS及癌症等與免疫反應之關聯。本課程適合修習過「組織學」、「生物化學」及「細胞生物學」的同學選修。授課方式以 powerpoint 講解大綱，同學必須閱讀英文教科書，並分組提問、討論與口頭報告。成績由多方面考核，包括準時出席、隨堂作答、小組參與、口頭報告、自發學習、小考、期中考及期末考。

The course will introduce the basic immune system and its functions, including innate and adaptive immune responses, the production of B lymphocytes and T lymphocytes, immune function mechanisms, and the relationship between the immune system and health and disease. Firstly, the cells, organs and innate immune system of the immune system are introduced, followed by topics such as antigens, antibodies, immunoglobulin gene composition, antigen-antibody reaction, complement, major histocompatibility complex, antigen presentation, maturation, activation and differentiation of T cells and B cells. The second half of the course discusses cytokines, leukocyte activation and movement, cellular toxic reactions, allergic reactions, immune tolerance and autoimmunity. Finally, the relationship between transplantation, infection, vaccines, AIDS, cancer, etc. and immune response will be discussed. This course is suitable for students who have studied "Histology", "Biochemistry" and "Cell Biology". The teaching method uses powerpoint to explain the outline. Students must read English textbooks and ask questions, discuss and give oral reports in groups. Achievements are assessed in many aspects, including punctual attendance, answering questions in class, group participation, oral presentations, spontaneous learning, quizzes, midterm exams and final exams.

1. Veterinary Immunology, Ian R. Tizard, 10th edition. Paperback ISBN: 9780323523493, eBook ISBN: 9780323523486, https://www.elsevier.com/books/veterinary-immunology/tizard/978-0-323-52349-3
2. Basic Immunology, Abul Abbas, Andrew Lichtman, Shiv Pillai, 7th edition. Paperback ISBN: 9780443105197, eBook ISBN: 9780443105500. https://www.elsevier.com/books/basic-immunology/abbas/978-0-443-10519-7

1. Veterinary Immunology, Ian R. Tizard, 10th edition. Paperback ISBN: 9780323523493, eBook ISBN: 9780323523486, https://www.elsevier.com/books/veterinary-immunology/tizard/978-0-323-52349-3
2. Basic Immunology, Abul Abbas, Andrew Lichtman, Shiv Pillai, 7th edition. Paperback ISBN: 9780443105197, eBook ISBN: 9780443105500. https://www.elsevier.com/books/basic-immunology/abbas/978-0-443-10519-7