6715 - 外泌體與細胞外囊泡生物學
Exosome and Extracellular Vesicle Biology
教育目標 Course Target
理解外泌體(Exosomes)與其他細胞外囊泡(EVs)之生物生成、組成與通訊功能。
掌握外泌體的分離、純化、定量與特徵化方法及挑戰。
認識外泌體在疾病診斷、生物標誌與治療運用中的關鍵角色。
分析外泌體在蛋白質、胜肽與基因遞送的應用策略。
探討外泌體在癌症、神經退化疾病、免疫與寄生蟲疾病的轉譯應用。
評估外泌體製劑開發中的 GMP、生產放大、法規與倫理議題。
具備設計外泌體為基礎的研究或臨床應用專案能力。
Understand the biogenesis, composition and communication functions of exosomes and other extracellular vesicles (EVs).
Master the methods and challenges of isolation, purification, quantification, and characterization of exosomes.
Understand the critical role of exosomes in disease diagnosis, biomarkers and therapeutic applications.
Analyze the application strategies of exosomes in protein, peptide and gene delivery.
Explore the translational applications of exosomes in cancer, neurodegenerative diseases, immune and parasitic diseases.
Evaluate GMP, scale-up, regulatory and ethical issues in the development of exosome formulations.
Ability to design exosome-based research or clinical application projects.
參考書目 Reference Books
Dalapathi Gugulothu, Dharmendra Kumar Khatri, Lalitkumar K. Vora, William C.S. Cho. Exosome Communication: Advances in Research and Therapeutics for Health and Disease. 1st Edit. 2024. ISBN: 978-0443290527
Dalapathi Gugulothu, Dharmendra Kumar Khatri, Lalitkumar K. Vora, William C.S. Cho. Exosome Communication: Advances in Research and Therapeutics for Health and Disease. 1st Edit. 2024. ISBN: 978-0443290527
評分方式 Grading
| 評分項目 Grading Method |
配分比例 Percentage |
說明 Description |
|---|---|---|
|
期末報告 Final report |
100 | 期末報告 |
授課大綱 Course Plan
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課程資訊 Course Information
基本資料 Basic Information
- 課程代碼 Course Code: 6715
- 學分 Credit: 0-3
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上課時間 Course Time:Wednesday/6,7,8
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授課教師 Teacher:謝長奇
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修課班級 Class:畜產系4,碩博1,2
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選課備註 Memo:碩士班先修生可選修。
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