5420 - 細胞電生理專論(三)

Special Topics on Cellular Electrophysiology (III)

教育目標 Course Target

細胞的電生理活性由細胞膜表面離子通道之活動產生。在神經和肌肉細胞中離子通道具有引發、傳遞和中止電氣活性的功能。在其它非興奮性細胞中,離子通道也調控了許多關鍵的生理過程,例如:腎小管上水份的再吸收,胰島素自胰島腺體中的釋放,卵子受精的過程,以及免疫細胞的發育。本課程的目標在於透過研究文獻的閱讀,小組討論,以及實驗的操作,使學生逐漸具備獨立操作儀器設備的能力,以及獲取與離子通道研究相關領域中,最新的生理學,病理學,轉譯醫學的基礎知識,以養成細胞電生理基礎研究的能力。

The electrophysiological activity of cells is generated by the activity of ion channels on the cell membrane surface. Ion channels have the function of initiating, transmitting, and terminating electrical activity in nerve and muscle cells. In other non-excitable cells, ion channels also regulate many key physiological processes, such as the reabsorption of water in the renal tubules, the release of insulin from the pancreatic islet glands, the fertilization of eggs, and the development of immune cells. The goal of this course is to enable students to gradually acquire the ability to independently operate instruments and equipment through the reading of research literature, group discussions, and experimental operations, as well as to acquire the latest basic knowledge of physiology, pathology, and translational medicine in the fields related to ion channel research, so as to develop the ability to conduct basic research on cell electrophysiology.

參考書目 Reference Books

1. Recent literature in major journals
2. (Optional) Ion Channels of Excitable Membranes, Third Edition, by Bertil Hille, Sinauer Associates, 2001
http://www.amazon.com/Ionic-Channels-Excitable-Membranes-Bertil/dp/0878933212

1. Recent literature in major journals
2. (Optional) Ion Channels of Excitable Membranes, Third Edition, by Bertil Hille, Sinauer Associates, 2001
http://www.amazon.com/Ionic-Channels-Excitable-Membranes-Bertil/dp/0878933212

評分方式 Grading

評分項目
Grading Method
配分比例
Percentage
說明
Description
文獻閱讀與討論
Literature reading and discussion
50 原始文獻之閱讀,討論,與報告
實驗儀器操作
Experimental instrument operation
50 實驗儀器操作與學術研究之精神與態度

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課程資訊 Course Information

基本資料 Basic Information

  • 課程代碼 Course Code: 5420
  • 學分 Credit: 1-0
  • 上課時間 Course Time:
  • 授課教師 Teacher:
    陳仁祥
  • 修課班級 Class:
    生科碩博1,2
  • 選課備註 Memo:
    上課時間、地點另訂
選課狀態 Enrollment Status

目前選課人數 Current Enrollment: 6 人

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