Importance and diversity of proteins. Active and inactive conformations of proteins. Principles of molecular recognition and applications. Importance of enzyme inhibitors in the development of modern drugs. Suicide enzyme inactivators. Receptor-ligand interactions and cooperativity,
allosteric enzymes, Scatchard equation and the Hill equation, enzyme mechanisms, mechanisms of selected enzymes: catalase, superoxide dismutase, carbonic anhydrase, cytochrome P450, glutathione transferase, glutathione peroxidases, restriction endonucleases, etc. Mechanisms and clinical significance of protein folding.
Importance and diversity of proteins. Active and inactive conformations of proteins. Principles of molecular recognition and applications. Importance of energy inhibitors in the development of modern drugs. Suicide energy inactivators. Receptor-ligand interactions and cooperation,
allosteric enzymes, Scatchard equation and the Hill equation, enzyme mechanisms, mechanisms of selected enzymes: catalase, superoxide dismutase, carbonic anhydrase, cytochrome P450, glutathione transferase, glutathione peroxidases, restriction endonucleases, etc. Mechanisms and clinical significance of protein folding.
介紹胜太解離平衡反應,胜太之 Ramachandran 構象分析,酵素、
蛋白因子二級及三級結構。著重介紹各類酵素(如restriction endonucleases)
與受質結合及反應機轉。
Introduction to the analysis of the equilibrium reaction of Shengtai, Ramachandran structure analysis, enzyme,
Protein factor grade 2 and 3 structures. Focus on introducing various types of enzymes (such as restriction endonucleases)
Combining with quality and reactor.
參攷生化主要期刊,如 J. Biol. Chem., PNAS, Biochemistry, Nature, Science 等
Refer to major biochemistry journals such as J. Biol. Chem., PNAS, Biochemistry, Nature, Science, etc.
評分項目 Grading Method | 配分比例 Grading percentage | 說明 Description |
---|---|---|
期中考,期末考期中考,期末考 Midterm exam, final exam |
50 | 有小考及報告 |