5365 - 蛋白化學
Protein Chemistry
教育目標 Course Target
Importance and diversity of proteins. Active and inactive conformations of proteins. Principles of molecular recognition and applications. Importance of enzyme inhibitors in the development of modern drugs. Suicide enzyme inactivators. Receptor-ligand interactions and cooperativity,
allosteric enzymes, Scatchard equation and the Hill equation, enzyme mechanisms, mechanisms of selected enzymes: catalase, superoxide dismutase, carbonic anhydrase, cytochrome P450, glutathione transferase, glutathione peroxidases, restriction endonucleases, etc. Mechanisms and clinical significance of protein folding.
Importance and diversity of proteins. Active and inactive conformations of proteins. Principles of molecular recognition and applications. Importance of energy inhibitors in the development of modern drugs. Suicide energy inactivators. Receptor-ligand interactions and cooperation,
allosteric enzymes, Scatchard equation and the Hill equation, enzyme mechanisms, mechanisms of selected enzymes: catalase, superoxide dismutase, carbonic anhydrase, cytochrome P450, glutathione transferase, glutathione peroxidases, restriction endonucleases, etc. Mechanisms and clinical significance of protein folding.
課程概述 Course Description
介紹胜太解離平衡反應,胜太之 Ramachandran 構象分析,酵素、
蛋白因子二級及三級結構。著重介紹各類酵素(如restriction endonucleases)
與受質結合及反應機轉。
Introduction to the analysis of the equilibrium reaction of Shengtai, Ramachandran structure analysis, enzyme,
Protein factor grade 2 and 3 structures. Focus on introducing various types of enzymes (such as restriction endonucleases)
Combining with quality and reactor.
參考書目 Reference Books
參攷生化主要期刊,如 J. Biol. Chem., PNAS, Biochemistry, Nature, Science 等
Refer to major biochemistry journals such as J. Biol. Chem., PNAS, Biochemistry, Nature, Science, etc.
評分方式 Grading
評分項目 Grading Method |
配分比例 Percentage |
說明 Description |
---|---|---|
期中考,期末考 Midterm exam, final exam |
50 | 有小考及報告 |
授課大綱 Course Plan
點擊下方連結查看詳細授課大綱
Click the link below to view the detailed course plan
相似課程 Related Courses
無相似課程 No related courses found
課程資訊 Course Information
基本資料 Basic Information
- 課程代碼 Course Code: 5365
- 學分 Credit: 0-3
-
上課時間 Course Time:Thursday/2,3,4[CH012]
-
授課教師 Teacher:佘 亮
-
修課班級 Class:化學系化生組4,碩博1,2
-
選課備註 Memo:先修過生物化學,大四可選
交換生/外籍生選課登記
請點選上方按鈕加入登記清單,再等候任課教師審核。
Add this class to your wishlist by clicking the button above.