最新課程概述: Importance and diversity of proteins. Active and inactive conformations of proteins. Importance of enzyme inhibitors in the development of modern drugs.Suicide enzyme inactivators. Receptor-ligand interactions and cooperativity, allosteric enzymes, Scatchard equation and the Hill equation, enzyme mechanisms, mechanisms of selected enzymes: catalase, superoxide dismutase, carbonic anhydrase, cytochrome P450, glutathione transferase, glutathione peroxidases, restriction endonucleases, etc. Mechanisms and clinical significance of protein folding.
Protein-nucleic acid interactions.Latest course overview: Importance and diversity of proteins. Active and inactive conformations of proteins. Importance of enzyme inhibitors in the development of modern drugs.Suicide enzyme inactivators. Receptor-ligand interactions and cooperativity, allosteric enzymes, Scatchard equation and the Hill equation, enzyme mechanisms, mechanisms of selected enzymes: catalase, superoxide dismutase, carbonic anhydrase, cytochrome P450, glutathione transferase, glutathione peroxidases, restriction endonucleases, etc. Mechanisms and clinical significance of protein folding.
Protein-nucleic acid interactions.
介紹胜太解離平衡反應，胜太之 Ramachandran 構象分析，酵素、
蛋白因子二級及三級結構。著重介紹各類酵素(如restriction endonucleases)
與受質結合及反應機轉。
Introduction to Shouta’s dissociation equilibrium reaction, Shouta’s Ramachandran conformation analysis, enzymes,
Secondary and tertiary structure of protein factors. Focus on various types of enzymes (such as restriction endonucleases)
Combine with substrate and reaction mechanism.
Reference: SCI papers : 如 J. Biol. Chem.,JACS, PNAS, Biochemistry, Nature, Science 等
Reference: SCI papers: such as J. Biol. Chem., JACS, PNAS, Biochemistry, Nature, Science, etc.
| 評分項目 Grading Method | 配分比例 Grading percentage | 說明 Description |
|---|---|---|
| 期中考 期末考期中考 期末考 Midterm exam Final exam |
50 | 期中考 期末考各50% 小考另行通知 |
