5370 - 蛋白化學
Protein Chemistry
教育目標 Course Target
最新課程概述: Importance and diversity of proteins. Active and inactive conformations of proteins. Importance of enzyme inhibitors in the development of modern drugs.Suicide enzyme inactivators. Receptor-ligand interactions and cooperativity, allosteric enzymes, Scatchard equation and the Hill equation, enzyme mechanisms, mechanisms of selected enzymes: catalase, superoxide dismutase, carbonic anhydrase, cytochrome P450, glutathione transferase, glutathione peroxidases, restriction endonucleases, etc. Mechanisms and clinical significance of protein folding.
Protein-nucleic acid interactions.
Latest course overview: Importance and diversity of proteins. Active and inactive conformations of proteins. Importance of energy inhibitors in the development of modern drugs.Suicide energy inactivators. Receptor-ligand interactions and cooperation, allosteric enzymes, Scatchard equation and the Hill equation, enzyme mechanisms, mechanisms of selected enzymes: catalase, superoxide dismutase, carbonic anhydrase, cytochrome P450, glutatthione transferase, glutatthione peroxidases, restriction endonucleases, etc. Mechanisms and clinical significance of protein folding.
Protein-nucleic acid interactions.
課程概述 Course Description
介紹胜太解離平衡反應,胜太之 Ramachandran 構象分析,酵素、
蛋白因子二級及三級結構。著重介紹各類酵素(如restriction endonucleases)
與受質結合及反應機轉。
Introduction to the analysis of the equilibrium reaction of Shengtai, Ramachandran structure analysis, enzyme,
Protein factor grade 2 and 3 structures. Focus on introducing various types of enzymes (such as restriction endonucleases)
Combining with quality and reactor.
參考書目 Reference Books
Reference: SCI papers : 如 J. Biol. Chem.,JACS, PNAS, Biochemistry, Nature, Science 等
Reference: SCI papers: such as J. Biol. Chem., JACS, PNAS, Biochemistry, Nature, Science, etc.
評分方式 Grading
評分項目 Grading Method |
配分比例 Percentage |
說明 Description |
---|---|---|
期中考 期末考 Midterm exam Final exam |
50 | 期中考 期末考各50% 小考另行通知 |
授課大綱 Course Plan
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相似課程 Related Courses
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課程資訊 Course Information
基本資料 Basic Information
- 課程代碼 Course Code: 5370
- 學分 Credit: 0-3
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上課時間 Course Time:Tuesday/2,3,4[CH012]
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授課教師 Teacher:佘 亮
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修課班級 Class:化學系4,碩博1,2
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選課備註 Memo:需先修過生物化學,大四可選修
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