5372 - 蛋白質折疊與疾病
Protein Folding and Diseases
教育目標 Course Target
This course aims to broaden the knowledge of protein folding/misfolding and to relate it to the human diseases.
This course aims to broaden the knowledge of protein folding/misfolding and to relate it to the human diseases.
參考書目 Reference Books
1. Ken A. Dill and Justin L. MacCallum, The Protein-Folding Problem, 50 Years On. Science, 2012, p1042-1046.
2. F. Ulrich Hartl, Molecular Chaperons in Cellular Protein Folding, Nature, 1996, v.381, p571-580.
3. “The importance of protein folding” by Joachim Pietzsch
4. F. Ulrich Hartl, Protein Misfolding Diseases, Annu. Rev. Biochem. 2017, V.86, p21–26.
5. Fabrizio Chiti and Christopher M. Dobson, Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade, Annu. Rev. Biochem. 2017, V.86, p27–68.
6. Surabhi Mehra, Shruti Sahay and Samir K. Maji, BBA - Proteins and Proteomics,
https://doi.org/10.1016/j.bbapap.2019.03.001
7. Whitechurch B.C., Welton J.M., Collins S.J., Lawson V.A. (2017) Prion Diseases. In: Beart P., Robinson M., Rattray M., Maragakis N. (eds) Neurodegenerative Diseases. Advances in Neurobiology, vol 15. Springer, Cham
8. “ Treating protein folding diseases” by Sophie Petit-Zeman
1. Ken A. Dill and Justin L. MacCallum, The Protein-Folding Problem, 50 Years On. Science, 2012, p1042-1046.
2. F. Ulrich Hartl, Molecular Chaperons in Cellular Protein Folding, Nature, 1996, v.381, p571-580.
3. “The importance of protein folding” by Joachim Pietzsch
4. F. Ulrich Hartl, Protein Misfolding Diseases, Annu. Rev. Biochem. 2017, V.86, p21–26.
5. Fabrizio Chiti and Christopher M. Dobson, Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade, Annu. Rev. Biochem. 2017, V.86, p27–68.
6. Surabhi Mehra, Shruti Sahay and Samir K. Maji, BBA - Proteins and Proteomics,
https://doi.org/10.1016/j.bbapap.2019.03.001
7. Whitechurch B.C., Welton J.M., Collins S.J., Lawson V.A. (2017) Prion Diseases. In: Beart P., Robinson M., Rattray M., Maragakis N. (eds) Neurodegenerated Diseases. Advanceds in Neurobiology, vol 15. Springer, Cham
8. “ Treating protein folding diseases” by Sophie Petit-Zeman
評分方式 Grading
| 評分項目 Grading Method |
配分比例 Percentage |
說明 Description |
|---|---|---|
|
課堂 paper 閱讀準備 Class paper Reading preparation |
50 | |
|
期末考試 Final exam |
20 | |
|
期中考試 Midterm exam |
20 | |
|
出席 Attend |
10 |
授課大綱 Course Plan
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課程資訊 Course Information
基本資料 Basic Information
- 課程代碼 Course Code: 5372
- 學分 Credit: 1-0
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上課時間 Course Time:Thursday/7[CH012]
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授課教師 Teacher:吳雨珊
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修課班級 Class:化學系4,碩博1,2
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選課備註 Memo:大四可選
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