This course aims to broaden the knowledge of protein folding/misfolding and to relate it to the human diseases. This course aims to broaden T and knowledge of protein folding/MIS folding and to relate IT TOT and human diseases.
1. Ken A. Dill and Justin L. MacCallum, The Protein-Folding Problem, 50 Years On. Science, 2012, p1042-1046.
2. F. Ulrich Hartl, Molecular Chaperons in Cellular Protein Folding, Nature, 1996, v.381, p571-580.
3. “The importance of protein folding” by Joachim Pietzsch
4. F. Ulrich Hartl, Protein Misfolding Diseases, Annu. Rev. Biochem. 2017, V.86, p21–26.
5. Fabrizio Chiti and Christopher M. Dobson, Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade, Annu. Rev. Biochem. 2017, V.86, p27–68.
6. Surabhi Mehra, Shruti Sahay and Samir K. Maji, BBA - Proteins and Proteomics,
https://doi.org/10.1016/j.bbapap.2019.03.001
7. Whitechurch B.C., Welton J.M., Collins S.J., Lawson V.A. (2017) Prion Diseases. In: Beart P., Robinson M., Rattray M., Maragakis N. (eds) Neurodegenerative Diseases. Advances in Neurobiology, vol 15. Springer, Cham
8. “ Treating protein folding diseases” by Sophie Petit-Zeman
1. Ken A. Dill and Justin L. MacCallum, The Protein-Folding Problem, 50 Years On. Science, 2012, p1042-1046.
2. F. Ulrich Hartl, Molecular Chaperons in Cellular Protein Folding, Nature, 1996, v.381, p571-580.
3. “The importance of protein folding” by Joachim Pietzsch
4. F. Ulrich Hartl, Protein Misfolding Diseases, Annu. Rev. Biochem. 2017, V.86, p21–26.
5. Fabrizio Chiti and Christopher M. Dobson, Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade, Annu. Rev. Biochem. 2017, V.86, p27–68.
6. Surabhi Mehra, Shruti Sahay and Samir K. Maji, BBA - Proteins and Proteomics,
https://doi.org/10.1016/j.bbapap.2019.03.001
7. Whitechurch B.C., Welton J.M., Collins S.J., Lawson V.A. (2017) Prion Diseases. In: Beart P., Robinson M., Rattray M., Maragakis N. (eds) Neurodegenerative Diseases. Advances in Neurobiology, vol 15. Springer , Cham
8. “ Treating protein folding diseases” by Sophie Petit-Zeman
| 評分項目 Grading Method | 配分比例 Grading percentage | 說明 Description |
|---|---|---|
| 課堂 paper 閱讀準備課堂 paper 閱讀準備 Class paper reading preparation |
50 | |
| 期末考試期末考試 final exam |
20 | |
| 期中考試期中考試 midterm exam |
20 | |
| 出席出席 Attend |
10 |
