在人體的離子通道缺陷導致許多重要器官例如腦與肌肉細胞喪失了其正常的細胞功能. 而越來越多的研究發現許多近年來人類的重大疾病是由於負責傳導細胞興奮過程的離子通道具有基因上的突變缺陷等 . 此門課旨在介紹 離子通道上的遺傳缺陷所導致的疾病並以分子生物學的角度和蛋白質結構與功能的關係來闡釋基因突變所造成的致病機轉. 此外另會介紹用來醫治因基因缺陷所造成疾病的最新治療用藥.In human ion channel defects, many important organs, such as the brain and muscle cells, have lost their normal cell function. More and more studies have found that many major human diseases in recent years are due to the genetic mutation defects in ion channels that are responsible for transmissing cell activity processes. This course aims to introduce diseases caused by transmissible defects on ion channels and to stimulate pathogenic mechanisms caused by genetic mutations from the perspective of molecular biology and the relationship between protein structure and function. In addition, the latest treatment drugs for medical treatment of diseases caused by genetic defects will be introduced.
1.Ion Channel Diseases, Volume 63 (Advances in Genetics)
Guy Rouleau and Claudia Gaspar
Advances in Genetics (Book 63)
Publisher: Academic Press; 1 edition (December 25, 2008)
2. Ion channels and Disease
Frances M. Ashcroft
Publisher: Academic Press; 1 edition (October 25, 1999)
1.Ion Channel Diseases, Volume 63 (Advances in Genetics)
Guy Rouleau and Claudia Gaspar
Advanceds in Genetics (Book 63)
Publisher: Academic Press; 1 edition (December 25, 2008)
2. Ion channels and Disease
Frances M. Ashcroft
Publisher: Academic Press; 1 edition (October 25, 1999)
| 評分項目 Grading Method | 配分比例 Grading percentage | 說明 Description |
|---|---|---|
| 報告報告 report |
50 | |
| 課堂討論課堂討論 Class discussion |
50 |
