離子通道是一群多樣化的蛋白質分子，在細胞膜表面負責調控離子進出細胞膜的過程。舉例而言，在神經和肌肉細胞中離子通道具有引發、傳遞和中止電氣活性的功能。在其它非興奮性細胞中，離子通道也調控了許多關鍵的生理過程，例如：腎小管上水份的再吸收，胰島素自胰島腺體中的釋放，卵子受精的過程，以及免疫細胞的發育。本課程的目標在於透過研究文獻的閱讀，小組討論，以及實驗的操作，使學生逐漸具備獨立操作儀器設備的能力，以及獲取與離子通道研究相關領域中，最新的生理學，病理學，轉譯醫學的基礎知識，以期成為進階研究人員的基礎。Ion channels are a group of diverse protein molecules that are responsible for controlling the process of ion entering and leaving the cell membrane on the surface of the cell membrane. For example, ion channels have the functions of initiating, transmitting and aborting the gas activity in neurons and muscle cells. In other non-sustaining cells, ion channels also control many key physiological processes, such as reabsorption of water on the kidney tubules, release of insulin from pancreatic glands, the process of egg fertilization, and the development of immune cells. The purpose of this course is to gradually gain the ability to prepare independent operating instrument equipment through research literature, group discussion, and experiments, and enable students to gradually gain the latest basic knowledge of physiology, pathology, and translating medicine in the fields related to ion channel research, in order to become the foundation of advanced researchers.
1. Recent literature in major journals
2. (Optional) Ion Channels of Excitable Membranes, Third Edition, by Bertil Hille, Sinauer Associates, 2001
http://www.amazon.com/Ionic-Channels-Excitable-Membranes-Bertil/dp/0878933212
1. Recent literature in major journals
2. (Optional) Ion Channels of Excitable Membranes, Third Edition, by Bertil Hille, Sinauer Associates, 2001
http://www.amazon.com/Ionic-Channels-Excitable-Membranes-Bertil/dp/0878933212
| 評分項目 Grading Method | 配分比例 Grading percentage | 說明 Description |
|---|---|---|
| 文獻閱讀與討論文獻閱讀與討論 Reading and discussion |
50 | 原始文獻之閱讀，討論，與報告 |
| 實驗儀器操作實驗儀器操作 Experimental instrument operation |
50 | 實驗儀器操作與學術研究之精神與態度 |
